A simulation model for analyzing brain structures deformations

Di Bona S., Lutzemberger L., Salvetti O.

3D images  Deformation analysis  Brain modeling 

Recent developments of medical software applications,from the simulation to the planning of surgical operations,have revealed the need for modelling human tissues and organs, not only from a geometric point of viewbut also from a physical one, i.e. soft tissues, rigid body, viscoelasticity, etc. This has given rise to the term 'deformable objects', which refers to objects with a morphology, a physical and a mechanical behaviour of their own and that reflects their natural properties. In this paper, we propose a model, based upon physical laws, suitable for the realistic manipulation of geometric reconstructions of volumetric data taken from MR and CT scans. In particular, a physically based model of the brain is presented that is able to simulate the evolution of different nature pathological intra-cranial phenomena such as haemorrhages, neoplasm, haematoma, etc and to describe the consequences that are caused by their volume expansions and the influences they have on the anatomical and neuro-functional structures of the brain.

Source: Physics in medicine and biology (Print) 48 (2003): 4001–4002.

Publisher: Institute of Physics., Bristol , Regno Unito