2012
Conference article  Restricted

Modeling enzymatic reactions via chemical Langevin-Levy equation.

Altinkaya M., Kuruoglu E. E.

Chemical Langevin equation  Levy flights  Current concentration  Detailed kinetics  Enzymatic reaction 

Chemical Langevin Equation (CLE) describes a useful approximation in stochastic modeling of chemical reactions. CLE-based ?-leaping algoritm updates the quantities of every molecule in a reaction system with a period of ?, firing every reaction in the system so many times that the concentration of each molecule can be assumed to remain in the current concentration state. Substituting the Brownian motion in the CLE with a Levy flight, one might expect the CLE to converge more rapidly. This work shows that alpha (Levy)-stable increments can be used in ?-leaping, demonstrating it with the example of a detailed kinetic model describing the enzymatic transgalactosylation reaction during lactulose hydrolysis.

Source: Signal Processing and Applications Conference, pp. 1–4, Fethiye, Turchia, 18-20 Aprile 2012

Publisher: IEEE Computer Society, Los Alamitos [CA], USA


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BibTeX entry
@inproceedings{oai:it.cnr:prodotti:220764,
	title = {Modeling enzymatic reactions via chemical Langevin-Levy equation.},
	author = {Altinkaya M. and Kuruoglu E.  E.},
	publisher = {IEEE Computer Society, Los Alamitos [CA], USA},
	doi = {10.1109/siu.2012.6204746},
	booktitle = {Signal Processing and Applications Conference, pp. 1–4, Fethiye, Turchia, 18-20 Aprile 2012},
	year = {2012}
}