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2026
Journal article
Open Access
Robustness of complexity estimation in event-driven signals against accuracy of event detection method
Cafiso Marco, Paradisi Paolo
Complexity has gained recent attention in machine learning for its ability to extract synthetic information from large datasets. Complex dynamical systems are characterized by temporal complexity associated with intermittent birth–death events of self-organizing behavior. These rapid transition events (RTEs) can be modeled as a stochastic point process on the time axis, with inter-event times (IETs) revealing rich dynamics. In particular, IETs with power-law distribution mark a departure from the Poisson statistics and indicate the presence of nontrivial complexity that is quantified by the power-law exponent μ of the IET distribution. However, detection of RTEs in noisy signals remains a challenge, since false positives can obscure the statistical structure of the underlying process. In this paper, we address the problem of quantifying the effect of the event detection tool on the accuracy of complexity estimation. This is reached through a systematic evaluation of the Event-Driven Diffusion Scaling (EDDiS) algorithm, a tool exploiting event-driven diffusion to estimate temporal complexity. After introducing the event detection method RTE-Finder (RTEF), we assess the performance of the RTEF-EDDiS pipeline using event-driven synthetic signals. The reliability of the RTEF is found to strongly depend on parameters such as the percentile and the number of false positives can be much higher than the number of genuine complex events. Despite this, we found that the complexity estimation is quite robust with respect to the rate of false positives. In many of the studied cases, the second moment scaling H appears to even improve as the rate of false positives increases, reaching estimation errors of about 4−7%.Source: CHAOS, SOLITONS AND FRACTALS, vol. 208 (issue 118264)
DOI: 10.1016/j.chaos.2026.118264
DOI: 10.2139/ssrn.5342885
DOI: 10.48550/arxiv.2506.06168
Project(s): Future Artificial Intelligence Research - Spoke 1 “Human-centered AI”
Metrics:
Cafiso Marco, Paradisi Paolo
Complexity has gained recent attention in machine learning for its ability to extract synthetic information from large datasets. Complex dynamical systems are characterized by temporal complexity associated with intermittent birth–death events of self-organizing behavior. These rapid transition events (RTEs) can be modeled as a stochastic point process on the time axis, with inter-event times (IETs) revealing rich dynamics. In particular, IETs with power-law distribution mark a departure from the Poisson statistics and indicate the presence of nontrivial complexity that is quantified by the power-law exponent μ of the IET distribution. However, detection of RTEs in noisy signals remains a challenge, since false positives can obscure the statistical structure of the underlying process. In this paper, we address the problem of quantifying the effect of the event detection tool on the accuracy of complexity estimation. This is reached through a systematic evaluation of the Event-Driven Diffusion Scaling (EDDiS) algorithm, a tool exploiting event-driven diffusion to estimate temporal complexity. After introducing the event detection method RTE-Finder (RTEF), we assess the performance of the RTEF-EDDiS pipeline using event-driven synthetic signals. The reliability of the RTEF is found to strongly depend on parameters such as the percentile and the number of false positives can be much higher than the number of genuine complex events. Despite this, we found that the complexity estimation is quite robust with respect to the rate of false positives. In many of the studied cases, the second moment scaling H appears to even improve as the rate of false positives increases, reaching estimation errors of about 4−7%.Source: CHAOS, SOLITONS AND FRACTALS, vol. 208 (issue 118264)
DOI: 10.1016/j.chaos.2026.118264
DOI: 10.2139/ssrn.5342885
DOI: 10.48550/arxiv.2506.06168
Project(s): Future Artificial Intelligence Research - Spoke 1 “Human-centered AI”
Metrics:
See at:
arXiv.org e-Print Archive 
| Chaos Solitons & Fractals | CNR IRIS | www.sciencedirect.com | doi.org 
| doi.org | CNR IRIS
2026
Conference article
Open Access
Advancements in Artificial Intelligence and Computer Vision for Biomedical Applications @SI-Lab
Marco Cafiso, Andrea Carboni, Claudia Caudai, Sara Colantonio, Francesco Conti, Mario D’acunto, Said Daoudagh, Giulio Del Corso, Riccardo Del Gratta, Danila Germanese, Giacomo Ignesti, Gianmarco Lazzini, Giuseppe Riccardo Leone, Barbara Leporini, Massimo Magrini, Massimo Martinelli, Davide Moroni, Ali Reza Omrani, Francesca Pardini, Maria Antonietta Pascali, Paolo Paradisi, Laura Sebastiaini, Marco Tampucci, Valeria Tateo, Federico Volpini
This paper summarizes recent research at the Signals and Images Lab (ISTI-CNR) leveraging artificial intelligence, machine learning, and computer vision to address complex biomedical challenges. We highlight advancements in trustworthy, explainable algorithmic foundations alongside their practical clinical applications across diagnostic imaging, physiological signal analysis and neuromotor rehabilitation.
Marco Cafiso, Andrea Carboni, Claudia Caudai, Sara Colantonio, Francesco Conti, Mario D’acunto, Said Daoudagh, Giulio Del Corso, Riccardo Del Gratta, Danila Germanese, Giacomo Ignesti, Gianmarco Lazzini, Giuseppe Riccardo Leone, Barbara Leporini, Massimo Magrini, Massimo Martinelli, Davide Moroni, Ali Reza Omrani, Francesca Pardini, Maria Antonietta Pascali, Paolo Paradisi, Laura Sebastiaini, Marco Tampucci, Valeria Tateo, Federico Volpini
This paper summarizes recent research at the Signals and Images Lab (ISTI-CNR) leveraging artificial intelligence, machine learning, and computer vision to address complex biomedical challenges. We highlight advancements in trustworthy, explainable algorithmic foundations alongside their practical clinical applications across diagnostic imaging, physiological signal analysis and neuromotor rehabilitation.
2025
Other
Open Access
SI-Lab Annual Research Report 2024
Awais Ch Muhammad, Baiamonte A., Benassi A., Berti A., Bertini G., Buongiorno R, Bulotta D., Cafiso M., Carboni A., Carloni G., Caudai C., Colantonio S., Conti F., Daoudagh S., Del Corso G., Fusco G., Galesi G., Germanese D., Gravili S., Ignesti G., Kuruoglu E. E., Lazzini G., Leone G. R., Leporini B., Magrini M., Martinelli M., Omrani Ali Reza, Pachetti E., Papini O., Paradisi P., Pardini F., Pascali M. A., Pieri G., Reggiannini M., Righi M., Salerno E., Salvetti O., Scozzari A., Sebastiani L., Straface S., Tampucci M., Tarabella L., Tonazzini A., Moroni D.
The Signal & Images Laboratory (SI-Lab) is an interdisciplinary research group in computer vision, signal analysis, intelligent vision systems and multimedia data understanding. It is part of the Institute of Information Science and Technologies (ISTI) of the National Research Council of Italy (CNR). This report accounts for the research activities of the Signal and Images Laboratory of the Institute of Information Science and Technologies during the year 2024.DOI: 10.32079/isti-ar-2025/002
Metrics:
Awais Ch Muhammad, Baiamonte A., Benassi A., Berti A., Bertini G., Buongiorno R, Bulotta D., Cafiso M., Carboni A., Carloni G., Caudai C., Colantonio S., Conti F., Daoudagh S., Del Corso G., Fusco G., Galesi G., Germanese D., Gravili S., Ignesti G., Kuruoglu E. E., Lazzini G., Leone G. R., Leporini B., Magrini M., Martinelli M., Omrani Ali Reza, Pachetti E., Papini O., Paradisi P., Pardini F., Pascali M. A., Pieri G., Reggiannini M., Righi M., Salerno E., Salvetti O., Scozzari A., Sebastiani L., Straface S., Tampucci M., Tarabella L., Tonazzini A., Moroni D.
The Signal & Images Laboratory (SI-Lab) is an interdisciplinary research group in computer vision, signal analysis, intelligent vision systems and multimedia data understanding. It is part of the Institute of Information Science and Technologies (ISTI) of the National Research Council of Italy (CNR). This report accounts for the research activities of the Signal and Images Laboratory of the Institute of Information Science and Technologies during the year 2024.DOI: 10.32079/isti-ar-2025/002
Metrics:
2025
Other
Open Access
ISTI-day 2025 Proceedings
Del Corso G., Pedrotti A., Federico G., Gennaro C., Carrara F., Amato G., Di Benedetto M., Gabrielli E., Belli D., Matrullo Zoe, Miori V., Tolomei Gabriele, Waheed T., Marchetti E., Calabrò Antonello., Rossetti G., Stella Massimo, Cazabet Rémy, Abramski K., Cau E., Citraro S., Failla A., Mesina V., Morini V., Pansanella V., Colantonio S., Germanese D., Pascali M. A., Bianchi L., Messina N., Falchi F., Barsellotti L., Pacini G., Cassese M., Puccetti G., Esuli A., Volpi L., Moreo Alejandro, Sebastiani F., Sperduti G., Nguyen Dong, Broccia G., Ter Beek M. H., Ferrari A., Massink M., Belmonte Gina, Ciancia V., Papini O., Canapa G., Catricalà B., Manca M., Paternò F., Santoro C., Zedda E., Gallo S., Maenza S., Mattioli A., Simeoli L., Rucci D., Carlini E., Dazzi P., Kavalionak H., Mordacchini M., Rulli C., Muntean Cristina Ioana, Nardini F. M., Perego R., Rocchietti G., Lettich F., Renso C., Pugliese C., Casini G., Haldimann Jonas, Meyer Thomas, Assante M., Candela L., Dell'Amico A., Frosini L., Mangiacrapa F., Oliviero A., Pagano P., Panichi G., Peccerillo B., Procaccini M., Mannocci A., Manghi P., Lonetti F., Kang Dongjae, Di Giandomenico F., Jee Eunkyoung, Lazzini G., Conti F., Scopigno R., D'Acunto M., Moroni D., Cafiso M., Paradisi P., Callieri M., Pavoni G., Corsini M., De Falco A., Sala F., Saraceni Q., Gattiglia Gabriele
ISTI-Day is an annual information and networking event organized by the Institute of Information Science and Technologies "A. Faedo" (ISTI) of the Italian National Research Council (CNR). This event features an opening talk of the Director of the Dept. DIITET (Emilio F. Campana) as well as an overview of the Institute's activities presented by the ISTI Director (Roberto Scopigno). Those institutional segments are complemented by dedicated presentations and round tables featuring former staff members, as well as internal and external collaborators. To foster a network of knowledge and collaboration among newcomers, the 2025 ISTI Day edition also includes a large poster session that provides a comprehensive overview of current research activities. Each of the 13 laboratories contributes 1–3 posters, highlighting the most innovative work and offering early-career researchers a platform for discussion. Thus these proceedings include the posters selected for ISTI-Day 2025, reflecting the diverse and innovative nature of the Institute's research.
Del Corso G., Pedrotti A., Federico G., Gennaro C., Carrara F., Amato G., Di Benedetto M., Gabrielli E., Belli D., Matrullo Zoe, Miori V., Tolomei Gabriele, Waheed T., Marchetti E., Calabrò Antonello., Rossetti G., Stella Massimo, Cazabet Rémy, Abramski K., Cau E., Citraro S., Failla A., Mesina V., Morini V., Pansanella V., Colantonio S., Germanese D., Pascali M. A., Bianchi L., Messina N., Falchi F., Barsellotti L., Pacini G., Cassese M., Puccetti G., Esuli A., Volpi L., Moreo Alejandro, Sebastiani F., Sperduti G., Nguyen Dong, Broccia G., Ter Beek M. H., Ferrari A., Massink M., Belmonte Gina, Ciancia V., Papini O., Canapa G., Catricalà B., Manca M., Paternò F., Santoro C., Zedda E., Gallo S., Maenza S., Mattioli A., Simeoli L., Rucci D., Carlini E., Dazzi P., Kavalionak H., Mordacchini M., Rulli C., Muntean Cristina Ioana, Nardini F. M., Perego R., Rocchietti G., Lettich F., Renso C., Pugliese C., Casini G., Haldimann Jonas, Meyer Thomas, Assante M., Candela L., Dell'Amico A., Frosini L., Mangiacrapa F., Oliviero A., Pagano P., Panichi G., Peccerillo B., Procaccini M., Mannocci A., Manghi P., Lonetti F., Kang Dongjae, Di Giandomenico F., Jee Eunkyoung, Lazzini G., Conti F., Scopigno R., D'Acunto M., Moroni D., Cafiso M., Paradisi P., Callieri M., Pavoni G., Corsini M., De Falco A., Sala F., Saraceni Q., Gattiglia Gabriele
ISTI-Day is an annual information and networking event organized by the Institute of Information Science and Technologies "A. Faedo" (ISTI) of the Italian National Research Council (CNR). This event features an opening talk of the Director of the Dept. DIITET (Emilio F. Campana) as well as an overview of the Institute's activities presented by the ISTI Director (Roberto Scopigno). Those institutional segments are complemented by dedicated presentations and round tables featuring former staff members, as well as internal and external collaborators. To foster a network of knowledge and collaboration among newcomers, the 2025 ISTI Day edition also includes a large poster session that provides a comprehensive overview of current research activities. Each of the 13 laboratories contributes 1–3 posters, highlighting the most innovative work and offering early-career researchers a platform for discussion. Thus these proceedings include the posters selected for ISTI-Day 2025, reflecting the diverse and innovative nature of the Institute's research.
See at:
CNR IRIS | www.isti.cnr.it | CNR IRIS
2025
Conference article
Open Access
Leveraging AI for Signal and Image Analysis in Medicine and Health
Marco Cafiso, Andrea Carboni, Claudia Caudai, Sara Colantonio, Francesco Conti, Mario D’acunto, Said Daoudagh, Giulio Del Corso, Danila Germanese, Giacomo Ignesti, Gianmarco Lazzini, Giuseppe Riccardo Leone, Massimo Magrini, Davide Moroni, Francesca Pardini, Maria Antonietta Pascali, Paolo Paradisi, Federico Volpini
The integration of artificial intelligence (AI) into the medical domain is driving innovation and progress in healthcare. This paper summarizes the research activities that a multidisciplinary research group within the Signals and Images Lab of the Institute of Information Science and Technologies of the National Research Council of Italy is carrying out to explore the great potential of AI in several applications, e.g., in the analysis of biomedical data, and in the development of tools for enhancing trustworthiness and reliability of AI based systems. From cancer diagnosis and grading, to the analysis of body physiological signals to improve the understanding of dance movement therapy as an approach to healthy aging, this work highlights the paradigm shift that AI has brought into medicine and healthcare.Source: CEUR WORKSHOP PROCEEDINGS, vol. 4121. Trieste, June 23-24, 2025
Marco Cafiso, Andrea Carboni, Claudia Caudai, Sara Colantonio, Francesco Conti, Mario D’acunto, Said Daoudagh, Giulio Del Corso, Danila Germanese, Giacomo Ignesti, Gianmarco Lazzini, Giuseppe Riccardo Leone, Massimo Magrini, Davide Moroni, Francesca Pardini, Maria Antonietta Pascali, Paolo Paradisi, Federico Volpini
The integration of artificial intelligence (AI) into the medical domain is driving innovation and progress in healthcare. This paper summarizes the research activities that a multidisciplinary research group within the Signals and Images Lab of the Institute of Information Science and Technologies of the National Research Council of Italy is carrying out to explore the great potential of AI in several applications, e.g., in the analysis of biomedical data, and in the development of tools for enhancing trustworthiness and reliability of AI based systems. From cancer diagnosis and grading, to the analysis of body physiological signals to improve the understanding of dance movement therapy as an approach to healthy aging, this work highlights the paradigm shift that AI has brought into medicine and healthcare.Source: CEUR WORKSHOP PROCEEDINGS, vol. 4121. Trieste, June 23-24, 2025
See at:
ceur-ws.org | CNR IRIS | CNR IRIS
2024
Conference article
Open Access
Temporal complexity of a Hopfield-type neural model in random and scale-free graphs
Cafiso M., Paradisi P.
The Hopfield network model and its generalizations were introduced as a model of associative, or contentaddressable, memory. They were widely investigated both as an unsupervised learning method in artificial intelligence and as a model of biological neural dynamics in computational neuroscience. The complexity features of biological neural networks have attracted the scientific community’s interest for the last two decades. More recently, concepts and tools borrowed from complex network theory were applied to artificial neural networks and learning, thus focusing on the topological aspects. However, the temporal structure is also a crucial property displayed by biological neural networks and investigated in the framework of systems displaying complex intermittency. The Intermittency-Driven Complexity (IDC) approach indeed focuses on the metastability of self-organized states, whose signature is a power-decay in the inter-event time distribution or a scaling behaviour in the related event-driven diffusion processes. The investigation of IDC in neural dynamics and its relationship with network topology is still in its early stages. In this work, we present the preliminary results of an IDC analysis carried out on a bio-inspired Hopfield-type neural network comparing two different connectivities, i.e., scale-free vs. random network topology. We found that random networks can trigger complexity features similar to that of scale-free networks, even if with some differences and for different parameter values, in particular for different noise levelsDOI: 10.5220/0013007600003837
DOI: 10.48550/arxiv.2406.12895
Project(s): FAIR “Future Artificial Intelligence Research”, Spoke-8: Pervasive AI.
Metrics:
Cafiso M., Paradisi P.
The Hopfield network model and its generalizations were introduced as a model of associative, or contentaddressable, memory. They were widely investigated both as an unsupervised learning method in artificial intelligence and as a model of biological neural dynamics in computational neuroscience. The complexity features of biological neural networks have attracted the scientific community’s interest for the last two decades. More recently, concepts and tools borrowed from complex network theory were applied to artificial neural networks and learning, thus focusing on the topological aspects. However, the temporal structure is also a crucial property displayed by biological neural networks and investigated in the framework of systems displaying complex intermittency. The Intermittency-Driven Complexity (IDC) approach indeed focuses on the metastability of self-organized states, whose signature is a power-decay in the inter-event time distribution or a scaling behaviour in the related event-driven diffusion processes. The investigation of IDC in neural dynamics and its relationship with network topology is still in its early stages. In this work, we present the preliminary results of an IDC analysis carried out on a bio-inspired Hopfield-type neural network comparing two different connectivities, i.e., scale-free vs. random network topology. We found that random networks can trigger complexity features similar to that of scale-free networks, even if with some differences and for different parameter values, in particular for different noise levelsDOI: 10.5220/0013007600003837
DOI: 10.48550/arxiv.2406.12895
Project(s): FAIR “Future Artificial Intelligence Research”, Spoke-8: Pervasive AI.
Metrics:
See at:
arXiv.org e-Print Archive | CNR IRIS | ncta.scitevents.org | doi.org | doi.org | Archivio della Ricerca - Università di Pisa | CNR IRIS