2022
Conference article  Open Access

Data models for an imaging bio-bank for colorectal, prostate and gastric cancer: the NAVIGATOR project

Berti A., Carloni G., Colantonio S., Pascali M. A., Manghi P., Pagano P., Buongiorno R., Pachetti E., Caudai C., Di Gangi D., Carlini E., Falaschi Z., Ciarrocchi E., Neri E., Bertelli E., Miele V., Carpi R., Bagnacci G., Di Meglio N., Mazzei M. A., Barucci A.

Data models  Entity-relationship diagram  Imaging bio-banks 

Researchers nowadays may take advantage of broad collections of medical data to develop personalized medicine solutions. Imaging bio-banks play a fundamental role, in this regard, by serving as organized repositories of medical images associated with imaging biomarkers. In this context, the NAVIGATOR Project aims to advance colorectal, prostate, and gastric oncology translational research by leveraging quantitative imaging and multi-omics analyses. As Project's core, an imaging bio-bank is being designed and implemented in a web-accessible Virtual Research Environment (VRE). The VRE serves to extract the imaging biomarkers and further process them within prediction algorithms. In our work, we present the realization of the data models for the three cancer use-cases of the Project. First, we carried out an extensive requirements analysis to fulfill the necessities of the clinical partners involved in the Project. Then, we designed three separate data models utilizing entity-relationship diagrams. We found diagrams' modeling for colorectal and prostate cancers to be more straightforward, while gastric cancer required a higher level of complexity. Future developments of this work would include designing a common data model following the Observational Medical Outcomes Partnership Standards. Indeed, a common data model would standardize the logical infrastructure of data models and make the bio-bank easily interoperable with other bio-banks.

Source: BHI '22 - IEEE-EMBS International Conference on Biomedical and Health Informatics, Ioannina, Greece, 27-30/09/2022

Publisher: IEEE - Institute of Electrical and Electronics Engineers, Piscataway, N.J., USA

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BibTeX entry
@inproceedings{oai:it.cnr:prodotti:471570,
	title = {Data models for an imaging bio-bank for colorectal, prostate and gastric cancer: the NAVIGATOR project},
	author = {Berti A. and Carloni G. and Colantonio S. and Pascali M. A. and Manghi P. and Pagano P. and Buongiorno R. and Pachetti E. and Caudai C. and Di Gangi D. and Carlini E. and Falaschi Z. and Ciarrocchi E. and Neri E. and Bertelli E. and Miele V. and Carpi R. and Bagnacci G. and Di Meglio N. and Mazzei M. A. and Barucci A.},
	publisher = {IEEE - Institute of Electrical and Electronics Engineers, Piscataway, N.J., USA},
	doi = {10.1109/bhi56158.2022.9926910},
	booktitle = {BHI '22 - IEEE-EMBS International Conference on Biomedical and Health Informatics, Ioannina, Greece, 27-30/09/2022},
	year = {2022}
}

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